Mounjaro Maker Is Cracking Down on Patients Taking It for Cosmetic Weight Loss
Ava White
Updated on February 23, 2026
Millions have turned to medication over the past year to lose weight, with four big names dominating the space: Ozempic, Mounjaro, Wegovy, and Zepbound. These drugs have skyrocketed in popularity amid the "Ozempic obsession" in Hollywood, with many celebs admitting to taking them in order to shed pounds quickly. But while manufacturers have largely stayed silent on the non-essential use of their medications, the maker of Mounjaro is now speaking out about patients taking the drug for cosmetic weight loss.
RELATED: Ozempic Competitor Mounjaro Is Becoming Even More Popular—Here's Why.
Eli Lilly is the company behind the tirzepatide medications Mounjaro and Zepbound. Mounjaro was approved by the U.S. Food and Drug Administration (FDA) first in 2022 as a treatment for adults with type 2 diabetes. And in November of last year, the FDA approved Zepbound for chronic weight management in adults with obesity.
In a new commercial released Feb. 23, the Mounjaro maker calls out patients who are taking these medications without meeting the approval requirements from the FDA. The ad, titled "Big Night," was released right before the March 10 Academy Awards, and features shots of things you would see at a Hollywood award ceremony: glittery gold dresses, red carpets, paparazzi, and the curtain rising in a theater.
"Some people have been using medicine never meant for them," a voiceover says. "For the smaller dress or tux. For a big night. For vanity. But that's not the point."
The ad then switches to a scene featuring a woman dressed in ordinary clothes taking public transit.
"People whose health is affected by obesity are the reason we work on these medications," the voiceover continues. "It matters who gets them."
While the commercial doesn't mention Mounjaro or Zepbound by name, Eli Lilly CEO David Ricks told CNN that it still works to deliver a message that the company is serious about.
"We have a point of view about how these drugs are being used," Ricks said. "These medicines were invented for people with a serious health condition; they were not invented just to have someone who's famous look a little bit better."
According to the latest data from the Centers for Disease Control and Prevention (CDC), obesity affects around 41.9 percent of adults in the U.S.
"This is a disease," Ricks told CNN. "It's a metabolic disorder that, for most people, won't go away without serious medical treatment … So I don't think we're going to make much progress on this topic, that affects 100 million-plus Americans, unless we treat it like a health condition just like we do hypertension or arrhythmia or anything else."
RELATED: Jillian Michaels' Big Ozempic Warning: It Makes You a "Prisoner for Life."
The CEO said that there are three specific reasons why Eli Lilly is cracking down on who gets access to popular weight-loss medications: insurance coverage, shortages, and the type of research that has gone into these drugs.
"We're a long way from being able to supply a billion people with these medications with obesity, let alone the people who may want to lose some weight cosmetically," Ricks told CNN. "So we need to prioritize, and that's what this ad's about, is prioritizing those who need it most."
The company also hasn't tested its weight-management-approved medication on patients who don't fall into one of the categories it is approved for.
"We've only studied it in a population that had overweight or obesity, and we've focused it on people with chronic complications from obesity," he explained. "We can't speak to benefits and risks outside the population, so we think it's only responsible to point the light here, where the drug is most needed."
Best Life offers the most up-to-date information from top experts, new research, and health agencies, but our content is not meant to be a substitute for professional guidance. When it comes to the medication you're taking or any other health questions you have, always consult your healthcare provider directly.
Kali Coleman Kali Coleman is a Senior Editor at Best Life. Her primary focus is covering news, where she often keeps readers informed on the ongoing COVID-19 pandemic and up-to-date on the latest retail closures.Read moreFiled UnderMedicine • News • Weight LossSources referenced in this articleRead This NextMounjaro Is Becoming Even More Popular
The active ingredient in Mounjaro, tirzepatide, could become a major bestseller, experts say.December 18, 2023Ozempic Patients Reveal Major Side Effect
Some who've used the drug say it can be hard to find ways to feel full.March 7, 20245 Antioxidant-Rich Foods for Weight Loss
These nutrient-dense foods can help you burn fat faster.March 2, 2024New Ozempic Competitor May Work Even Faster
A new drug from Viking Therapeutics produced results in just 13 weeks.March 1, 2024New Study Shows How to Quit Ozempic
Researchers believe they've found the answer to avoiding rebound weight gain.February 27, 2024Doctor Reveals New Ozempic Side Effect
Max Pemberton, MRCPsych, didn't expect this when he started on semaglutide.February 23, 2024Ozempic May Cause Dangerous Muscle Loss
There are a few steps you can take while still achieving your weight-loss goals.February 9, 2024Jillian Michaels Reveals Weight-Loss Hacks
They require some dedication, but you'll see results without worrying about side effects.February 7, 2024Ozempic Safer Than Tylenol, Terry Dubrow Says
The plastic surgeon is dedicated to correcting the narrative around Ozempic. February 1, 20243 Probiotics That Trigger Weight Loss
They can boost GLP-1 levels and improve your gut health.January 29, 2024